Réponses Moléculaires et Cellulaires aux Xénobiotiques (RMCX)


Sélection de publications

1/ Sanchez-Guzman D., Boland S., Brookes O., Mc Cord C., Lai Kuen R., Sirri V., Baeza Squiban A.*, Devineau S.* Long-term evolution of the epithelial cell secretome in preclinical 3D models of the human bronchial epithelium. Sci Rep. 2021, 11:6621

2/ Brookes O., Boland S., Lai Kuen R., Movassat J., Baeza-Squiban A. Co-culture of type I and type II pneumocytes as a model of alveolar epithelium, Plos One. 2021 Sep 27;16(9):e0248798.

3/ Berthelet J, Michail C, Bui LC, Le Coadou L, Sirri V, Wang L, Dulphy N, Dupret JM, Chomienne C, Guidez F, Rodrigues-Lima F. The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3). Mol Pharmacol. 2021 Sep;100(3):283-294.

4/ Duval R, Bui LC, Mathieu C, Nian Q, Berthelet J, Xu X, Haddad I, Vinh J, Dupret JM, Busi F, Guidez F, Chomienne C, Rodrigues-Lima F. Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling. J Biol Chem. 2019 Aug 16;294(33):12483-12494.

5/ Mathieu C, Duval R, Cocaign A, Petit E, Bui LC, Haddad I, Vinh J, Etchebest C, Dupret JM, Rodrigues Lima F. An isozyme-specific redox switch in human brain glycogen phosphorylase modulates its allosteric activation by AMP. J Biol Chem. 2016 Sept 22. “Paper of the Week” of the Journal of Biological Chemistry


Publications dans des journaux à comité de lecture (depuis 2015)

Pareek V, Gupta R, Devineau S, Sivasankaran SK, Bhargava A, Khan MA, Srikumar S, Fanning S, Panwar J. Does Silver in Different Forms Affect Bacterial Susceptibility and Resistance? A Mechanistic Perspective. ACS Appl Bio Mater. 2022 Jan 25. doi: 10.1021/acsabm.1c01179. Epub ahead of print. PMID: 35073697.

Avet C, Paul EN, Garrel G, Grange-Messent V, L’Hôte D, Denoyelle C, Corre R, Dupret JM, Lanone S, Boczkowski J, Simon V, Cohen-Tannoudji J. Carbon Black Nanoparticles Selectively Alter Follicle-Stimulating Hormone Expression <i>in vitro</i> and <i>in vivo</i> in Female Mice. Front Neurosci. 2021 Dec 6;15:780698. doi: 10.3389/fnins.2021.780698. PMID: 34938157; PMCID: PMC8685435.

Brookes O, Boland S, Lai Kuen R, Miremont D, Movassat J, Baeza-Squiban A. Co- culture of type I and type II pneumocytes as a model of alveolar epithelium. PLoS One. 2021 Sep 27;16(9):e0248798. doi: 10.1371/journal.pone.0248798. PMID: 34570783; PMCID: PMC8475999.

Sanchez-Guzman D, Boland S, Brookes O, Mc Cord C, Lai Kuen R, Sirri V, Baeza Squiban A, Devineau S. Long-term evolution of the epithelial cell secretome in preclinical 3D models of the human bronchial epithelium. Sci Rep. 2021 Mar 23;11(1):6621. doi: 10.1038/s41598-021-86037-0. PMID: 33758289; PMCID: PMC7988136.

Zhang W, Lopez H, Boselli L, Bigini P, Perez-Potti A, Xie Z, Castagnola V, Cai Q, Silveira CP, de Araujo JM, Talamini L, Panini N, Ristagno G, Violatto MB, Devineau S, Monopoli MP, Salmona M, Giannone VA, Lara S, Dawson KA, Yan Y. A Nanoscale Shape-Discovery Framework Supporting Systematic Investigations of Shape-Dependent Biological Effects and Immunomodulation. ACS Nano. 2021 Dec 27. doi: 10.1021/acsnano.1c10074. Epub ahead of print. PMID: 34958549.

Deval G, Boland S, Fournier T, Ferecatu I. On Placental Toxicology Studies and Cerium Dioxide Nanoparticles. Int J Mol Sci. 2021 Nov 12;22(22):12266. doi: 10.3390/ijms222212266. PMID: 34830142; PMCID: PMC8624015.

Anes J, Dever K, Eshwar A, Nguyen S, Cao Y, Sivasankaran SK, Sakalauskaitė S, Lehner A, Devineau S, Daugelavičius R, Stephan R, Fanning S, Srikumar S. Analysis of the Oxidative Stress Regulon Identifies <i>soxS</i> as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae. mBio. 2021 Jun 29;12(3):e0086721. doi: 10.1128/mBio.00867-21. Epub 2021 Jun 8. PMID: 34098732; PMCID: PMC8262902.

Pareek V, Devineau S, Sivasankaran SK, Bhargava A, Panwar J, Srikumar S, Fanning S. Silver Nanoparticles Induce a <i>Triclosan-Like</i> Antibacterial Action Mechanism in Multi-Drug Resistant <i>Klebsiella pneumoniae</i>. Front Microbiol. 2021 Feb 15;12:638640. doi: 10.3389/fmicb.2021.638640. PMID: 33658987; PMCID: PMC7917072.

Hu Y, Anes J, Devineau S, Fanning S. <i>Klebsiella pneumoniae</i>: Prevalence, Reservoirs, Antimicrobial Resistance, Pathogenicity, and Infection: A Hitherto Unrecognized Zoonotic Bacterium. Foodborne Pathog Dis. 2021 Feb;18(2):63-84. doi: 10.1089/fpd.2020.2847. Epub 2020 Oct 30. PMID: 33124929.

Nian Q, Berthelet J, Parlato M, Mechaly AE, Liu R, Dupret JM, Cerf-Bensussan N, Haouz A, Rodrigues Lima F. Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy. Protein Sci. 2021 Nov 22. doi: 10.1002/pro.4246. Epub ahead of print. PMID: 34806245.

Liang S, Zhou X, Cai D, Rodrigues-Lima F, Chi J, Wang L. Network Pharmacology and Experimental Validation Reveal the Effects of Chidamide Combined With Aspirin on Acute Myeloid Leukemia-Myelodysplastic Syndrome Cells Through PI3K/AKT Pathway. Front Cell Dev Biol. 2021 Sep 9;9:685954. doi: 10.3389/fcell.2021.685954. PMID: 34568314; PMCID: PMC8458633.

Berthelet J, Michail C, Bui LC, Le Coadou L, Sirri V, Wang L, Dulphy N, Dupret JM, Chomienne C, Guidez F, Rodrigues-Lima F. The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3). Mol Pharmacol. 2021 Sep;100(3):283-294. doi: 10.1124/molpharm.121.000303. Epub 2021 Jul 15. PMID: 34266924.

Zhang W, Gou P, Dupret JM, Chomienne C, Rodrigues-Lima F. Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play. Transl Oncol. 2021 Oct;14(10):101169. doi: 10.1016/j.tranon.2021.101169. Epub 2021 Jul 6. PMID: 34243013; PMCID: PMC8273223.

Liang S, Zhou X, Cai D, Rodrigues-Lima F, Wang L. Chidamide Inhibits Cell Proliferation via the PI3K/AKT Pathway in K562 Cells Based on Network Pharmacology and Experimental Validation. Curr Pharm Des. 2021;27(26):2990-2998. doi: 10.2174/1381612827666210701152250. PMID: 34218775.

Cheeseman K, Jannot G, Lourenço N, Villares M, Berthelet J, Calegari-Silva T, Hamroune J, Letourneur F, Rodrigues-Lima F, Weitzman JB. Dynamic methylation of histone H3K18 in differentiating Theileria parasites. Nat Commun. 2021 May 28;12(1):3221. doi: 10.1038/s41467-021-23477-2. PMID: 34050145; PMCID: PMC8163883.

Zhang W, Berthelet J, Michail C, Bui LC, Gou P, Liu R, Duval R, Renault J, Dupret JM, Guidez F, Chomienne C, Rodrigues Lima F. Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues. Free Radic Biol Med. 2021 Jan;162:27-37. doi: 10.1016/j.freeradbiomed.2020.11.027. Epub 2020 Dec 2. PMID: 33278510.

Lizarralde-Iragorri MA, Lefevre SD, Cochet S, El Hoss S, Brousse V, Filipe A, Dussiot M, Azouzi S, Le Van Kim C, Rodrigues-Lima F, Français O, Le Pioufle B, Klei T, van Bruggen R, El Nemer W. Oxidative stress activates red cell adhesion to laminin in sickle cell disease. Haematologica. 2021 Sep 1;106(9):2478-2488. doi: 10.3324/haematol.2020.261586. PMID: 32855277; PMCID: PMC8409043.

Crobeddu B, Baudrimont I, Deweirdt J, Sciare J, Badel A, Camproux AC, Bui LC, Baeza-Squiban A. Lung Antioxidant Depletion: A Predictive Indicator of Cellular Stress Induced by Ambient Fine Particles. Environ Sci Technol. 2020 Feb 18;54(4):2360-2369. doi: 10.1021/acs.est.9b05990. Epub 2020 Jan 30. PMID: 31961142.

Radiom M, He Y, Peng-Wang J, Baeza-Squiban A, Berret JF, Chen Y. Alveolar mimics with periodic strain and its effect on the cell layer formation. Biotechnol Bioeng. 2020 Sep;117(9):2827-2841. doi: 10.1002/bit.27458. Epub 2020 Jun 27. PMID: 32542664.

Sanchez-Guzman D, Giraudon-Colas G, Marichal L, Boulard Y, Wien F, Degrouard J, Baeza-Squiban A, Pin S, Renault JP, Devineau S. <i>In Situ</i> Analysis of Weakly Bound Proteins Reveals Molecular Basis of Soft Corona Formation. ACS Nano. 2020 Jul 28;14(7):9073-9088. doi: 10.1021/acsnano.0c04165. Epub 2020 Jul 7. PMID: 32633939.

Nedder M, Boland S, Devineau S, Zerrad-Saadi A, Rogozarski J, Lai-Kuen R, Baya I, Guibourdenche J, Vibert F, Chissey A, Gil S, Coumoul X, Fournier T, Ferecatu I. Uptake of Cerium Dioxide Nanoparticles and Impact on Viability, Differentiation and Functions of Primary Trophoblast Cells from Human Placenta. Nanomaterials (Basel). 2020 Jul 3;10(7):1309. doi: 10.3390/nano10071309. PMID: 32635405; PMCID: PMC7407216.

Tada-Oikawa S, Eguchi M, Yasuda M, Izuoka K, Ikegami A, Vranic S, Boland S, Tran L, Ichihara G, Ichihara S. Functionalized Surface-Charged SiO<sub>2</sub> Nanoparticles Induce Pro-Inflammatory Responses, but Are Not Lethal to Caco-2 Cells. Chem Res Toxicol. 2020 May 18;33(5):1226-1236. doi: 10.1021/acs.chemrestox.9b00478. Epub 2020 May 8. PMID: 32319286.

Parlato M, Nian Q, Charbit-Henrion F, Ruemmele FM, Rodrigues-Lima F, Cerf-Bensussan N; Immunobiota Study Group. Loss-of-Function Mutation in PTPN2 Causes Aberrant Activation of JAK Signaling Via STAT and Very Early Onset Intestinal Inflammation. Gastroenterology. 2020 Nov;159(5):1968-1971.e4. doi: 10.1053/j.gastro.2020.07.040. Epub 2020 Jul 25. PMID: 32721438.

Xu X, Zhang W, Berthelet J, Liu R, Michail C, Chaffotte AF, Dupret JM, Rodrigues-Lima F. From transglutaminases (TGs) to arylamine N-acetyltransferases (NATs): Insight into the role of a spatially conserved aromatic amino acid position in the active site of these two families of enzymes. Biochem Biophys Res Commun. 2020 Apr 30;525(2):308-312. doi: 10.1016/j.bbrc.2020.02.082. Epub 2020 Feb 20. PMID: 32089267.

Busi F. Fluorescent Oligonucleotide Probes for the Quantification of RNA by Real-Time qPCR. Methods Mol Biol. 2020;2113:263-280. doi: 10.1007/978-1-0716-0278-2_18. PMID: 32006320.

Radiom M, Sarkis M, Brookes O, Oikonomou EK, Baeza-Squiban A, Berret JF. Pulmonary surfactant inhibition of nanoparticle uptake by alveolar epithelial cells. Sci Rep. 2020 Nov 10;10(1):19436. doi: 10.1038/s41598-020-76332-7. PMID: 33173147

Adon J., Liousse C., Doumbia T., Baeza-Squiban A., Cachier H., Leon F., Yoboue V., Akpo Ab., Galy-Lacaux C., Zoutien C., Xu H., Gardrat E., Keita S. (2020) Physico-chemical characterization of urban aerosols from specific combustion sources in West Africa at Abidjan in Côte d’Ivoire and Cotonou in Benin in the frame of DACCIWA program. Atmos. Chem. Phys; doi.org/10.5194/acp-2019-406

Barouki R, Kogevinas M, Audouze K, Belesova K, Bergman A, Birnbaum L, Boekhold S, Denys S, Desseille C, Drakvik E, Frumkin H, Garric J, Destoumieux-Garzon D, Haines A, Huss A, Jensen G, Karakitsios S, Klanova J, Koskela IM, Laden F, Marano F, Franziska Matthies-Wiesler E, Morris G, Nowacki J, Paloniemi R, Pearce N, Peters A, Rekola A, Sarigiannis D, Šebková K, Slama R, Staatsen B, Tonne C, Vermeulen R, Vineis P; HERA-COVID-19 working group. Electronic address: https://www.heraresearcheu.eu/. The COVID-19 pandemic and global environmental change: Emerging research needs. Environ Int. 2020 Nov 19;146:106272. doi: 10.1016/j.envint.2020.106272. Epub ahead of print. PMID: 33238229; PMCID: PMC7674147.

Vranic S, Shimada Y, Ichihara S, Kimata M, Wu W, Tanaka T, Boland S, Tran L, Ichihara G. Toxicological Evaluation of SiO₂ Nanoparticles by Zebrafish Embryo Toxicity Test. Int J Mol Sci. 2019 Feb 18;20(4).

Sirri V, Grob A, Berthelet J, Jourdan N, Roussel P. Sirtuin 7 promotes 45S pre-rRNA cleavage at site 2 and determines the processing pathway. J Cell Sci. 2019 Sep 2;132(17).

Mathieu C, Dupret JM, Rodrigues-Lima F. The Structure and the Regulation of Glycogen Phosphorylases in Brain. Adv Neurobiol. 2019;23:125-145.

Denis RGP, Busi F, Castel J, Morel C, Zhang W, Bui LC, Sugamori KS, Prokopec SD, Boutros PC, Grant DM, Rodrigues-Lima F, Luquet S, Dupret JM. A readout of metabolic efficiency in arylamine N-acetyltransferase-deficient mice reveals minor energy metabolism changes. FEBS Lett. 2019 Apr;593(8):831-841.

Duval R, Bui LC, Mathieu C, Nian Q, Berthelet J, Xu X, Haddad I, Vinh J, Dupret JM, Busi F, Guidez F, Chomienne C, Rodrigues-Lima F. Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signaling. J Biol Chem. 2019 Aug 16;294(33):12483-12494.

Nian Q, Berthelet J, Zhang W, Bui LC, Liu R, Xu X, Duval R, Ganesan S, Leger T, Chomienne C, Busi F, Guidez F, Dupret JM, Rodrigues Lima F. T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide. Mol Pharmacol. 2019 Aug;96(2):297-306.

Wakx A, Nedder M, Tomkiewicz-Raulet C, Dalmasso J, Chissey A, Boland S, Vibert F, Degrelle SA, Fournier T, Coumoul X, Gil S, Ferecatu I. Expression, Localization, and Activity of the Aryl Hydrocarbon Receptor in the Human Placenta. Int J Mol Sci. 2018 Nov 27;19(12).

London J, Ndiaye FK, Bui LC, Souchet B, Daubigney F, Magnan C, Luquet S, Dairou J, Janel N, Rouch C. Alterations in the Serotonin and Dopamine Pathways by Cystathionine Beta Synthase Overexpression in Murine Brain. Mol Neurobiol. 2019 Jun;56(6):3958-3971.

Malabirade A, Partouche D, El Hamoui O, Turbant F, Geinguenaud F, Recouvreux P, Bizien T, Busi F, Wien F, Arluison V. Revised role for Hfq bacterial regulator on DNA topology. Sci Rep. 2018 Nov 14;8(1):16792.

Devineau S, Kiger L, Galacteros F, Baudin-Creuza V, Marden M, Renault JP, Pin S. Manipulating hemoglobin oxygenation using silica nanoparticles: a novel prospect for artificial oxygen carriers. Blood Adv. 2018 Jan 23;2(2):90-94.

Sevin M, Kubovcakova L, Pernet N, Causse S, Vitte F, Villeval JL, Lacout C, Cordonnier M, Rodrigues-Lima F, Chanteloup G, Mosca M, Chrétien ML, Bastie JN, Audia S, Sagot P, Ramla S, Martin L, Gleave M, Mezger V, Skoda R, Plo I, Garrido C, Girodon F, de Thonel A. HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis. Nat Commun. 2018 Apr 12;9(1):1431.

Neumann F, Gourdain S, Albac C, Dekker AD, Bui LC, Dairou J, Schmitz-Afonso I, Hue N, Rodrigues-Lima F, Delabar JM, Potier MC, Le Caër JP, Touboul D, Delatour B, Cariou K, Dodd RH. DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives. Sci Rep. 2018 Feb 12;8(1):2859.

Puisney C, Oikonomou E, Nowak S, Chevillot A, Casale S, Baeza-Squiban A, Berret JF. Brake wear (nano)particle characterization and toxicity on airway epithelial cells in vitro. Environ Sci: Nano. 2018 ; 5 :1036-1044.

Puisney C, Baeza-Squiban A, Boland S. Mechanisms of Uptake and Translocation of Nanomaterials in the Lung. Adv Exp Med Biol. 2018;1048:21-36.

London J, Rouch C, Bui LC, Assayag E, Souchet B, Daubigney F, Medjaoui H, Luquet S, Magnan C, Delabar JM, Dairou J, Janel N. Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues. Mol Neurobiol. 2018 May;55(5):3822-3831.

Marano F. Mieux prendre en compte la santé environnementale. Soins. 2018 Mar;63(823):50.

Busi F, Arluison V, Régnier P. Absolute Regulatory Small Noncoding RNA Concentration and Decay Rates Measurements in Escherichia coli. Methods Mol Biol. 2018;1737:231-248.

Hellack B., Nickel C., Albrecht C., Kuhlbusch T.A.J., Boland S., Baeza-Squiban A., Wohlleben W., Schins R.P.F. Analytical methods to assess the oxidative potential of nanoparticles: a review. Environ Sci: Nano. 2017 ; 4:1920-1934.

Stone V, Miller MR, Clift MJD, Elder A, Mills NL, Møller P, Schins RPF, Vogel U, Kreyling WG, Alstrup Jensen K, Kuhlbusch TAJ, Schwarze PE, Hoet P, Pietroiusti A, De Vizcaya-Ruiz A, Baeza-Squiban A, Teixeira JP, Tran CL, Cassee FR. Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge. Environ Health Perspect. 2017 Oct 10;125(10):106002.

Mousseau F, Puisney C, Mornet S, Borgne RL, Vacher A, Airiau M, Baeza-Squiban A, Berret JF. Supported pulmonary surfactant bilayers on silica nanoparticles: formulation, stability and impact on lung epithelial cells. Nanoscale. 2017 Oct 12;9(39):14967-14978.

Deweirdt J, Quignard JF, Crobeddu B, Baeza-Squiban A, Sciare J, Courtois A, Lacomme S, Gontier E, Muller B, Savineau JP, Marthan R, Guibert C, Baudrimont I. Involvement of oxidative stress and calcium signaling in airborne particulate matter – induced damages in human pulmonary artery endothelial cells. Toxicol In Vitro. 2017 Dec;45(Pt 3):340-350.

Crobeddu B, Aragao-Santiago L, Bui LC, Boland S, Baeza Squiban A. Oxidative potential of particulate matter 2.5 as predictive indicator of cellular stress. Environ Pollut. 2017 Nov;230:125-133.

Vranic S, Gosens I, Jacobsen NR, Jensen KA, Bokkers B, Kermanizadeh A, Stone V, Baeza-Squiban A, Cassee FR, Tran L, Boland S. Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO(2) nanoparticles. Arch Toxicol. 2017 Jan;91(1):353-363.

García-Ramírez I, Tadros S, González-Herrero I, Martín-Lorenzo A, Rodríguez-Hernández G, Moore D, Ruiz-Roca L, Blanco O, Alonso-López D, Rivas JL, Hartert K, Duval R, Klinkebiel D, Bast M, Vose J, Lunning M, Fu K, Greiner T, Rodrigues-Lima F, Jiménez R, Criado FJG, Cenador MBG, Brindle P, Vicente-Dueñas C, Alizadeh A, Sánchez-García I, Green MR. Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice. Blood. 2017 May 11;129(19):2645-2656.

Simon V, Avet C, Grange-Messent V, Wargnier R, Denoyelle C, Pierre A, Dairou J, Dupret JM, Cohen-Tannoudji J. Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway. Endocrinology. 2017 Oct 1;158(10):3200-3211.

Xu X, Mathieu C, Berthelet J, Duval R, Bui LC, Busi F, Dupret JM, Rodrigues-Lima F. Human Arylamine N-Acetyltransferase 1 Is Inhibited by the Dithiocarbamate Pesticide Thiram. Mol Pharmacol. 2017 Sep;92(3):358-365.

Kubiak X, Duval R, Pluvinage B, Chaffotte AF, Dupret JM, Rodrigues-Lima F. Xenobiotic-metabolizing enzymes in Bacillus anthracis: molecular and functional analysis of a truncated arylamine N-acetyltransferase isozyme. Br J Pharmacol. 2017 Jul;174(14):2174-2182.

Mathieu C, Bui LC, Petit E, Haddad I, Agbulut O, Vinh J, Dupret JM, Rodrigues-Lima F. Molecular Mechanisms of Allosteric Inhibition of Brain Glycogen Phosphorylase by Neurotoxic Dithiocarbamate Chemicals. J Biol Chem. 2017 Feb 3;292(5):1603-1612.

Mathieu C, Dupret JM, Rodrigues Lima F. The structure of brain glycogen phosphorylase-from allosteric regulation mechanisms to clinical perspectives. FEBS J. 2017 Feb;284(4):546-554.

Delaval M, Wohlleben W, Landsiedel R, Baeza-Squiban A, Boland S. Assessment of the oxidative potential of nanoparticles by the cytochrome c assay: assay improvement and development of a high-throughput method to predict the toxicity of nanoparticles. Arch Toxicol. 2017 Jan;91(1):163-177.

Mathieu C, Duval R, Cocaign A, Petit E, Bui LC, Haddad I, Vinh J, Etchebest C, Dupret JM, Rodrigues Lima F. An isozyme-specific redox switch in human brain glycogen phosphorylase modulates its allosteric activation by AMP. J Biol Chem. 2016 Nov 11;291(46):23842-23853.

Mathieu C, de la Sierra-Gallay IL, Duval R, Xu X, Cocaign A, Léger T, Woffendin G, Camadro JM, Etchebest C, Haouz A, Dupret JM, Rodrigues-Lima F. Insights into Brain Glycogen Metabolism: THE STRUCTURE OF HUMAN BRAIN GLYCOGEN PHOSPHORYLASE. J Biol Chem. 2016 Aug 26;291(35):18072-83.

Sirri V, Jourdan N, Hernandez-Verdun D, Roussel P. Sharing of mitotic pre-ribosomal particles between daughter cells. J Cell Sci. 2016 Apr 15;129(8):1592-604.

Duval R, Xu X, Bui LC, Mathieu C, Petit E, Cariou K, Dodd RH, Dupret JM, Rodrigues-Lima F. Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens. Oncotarget. 2016 Feb 23;7(8):8688-99.

Bui LC, Tomkiewicz C, Pierre S, Chevallier A, Barouki R, Coumoul X. Regulation of Aquaporin 3 Expression by the AhR Pathway Is Critical to Cell Migration. Toxicol Sci. 2016 Jan;149(1):158-66.

Lovera-Leroux M, Crobeddu B, Kassis N, Petit PX, Janel N, Baeza-Squiban A, Andreau K. The iron component of particulate matter is antiapoptotic: A clue to the development of lung cancer after exposure to atmospheric pollutants? Biochimie. 2015 Nov;118:195-206.

Messaoudi N, Gautier V, Dairou J, Mihoub M, Lelandais G, Bouloc P, Landoulsi A, Richarme G. Fermentation and alternative respiration compensate for NADH dehydrogenase deficiency in a prokaryotic model of DJ-1-associated Parkinsonism. Microbiology. 2015 Nov;161(11):2220-31.

Gemble S, Ahuja A, Buhagiar-Labarchède G, Onclercq-Delic R, Dairou J, Biard DS, Lambert S, Lopes M, Amor-Guéret M. Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA. PLoS Genet. 2015 Jul 16;11(7):e1005384.

Mihoub M, Abdallah J, Gontero B, Dairou J, Richarme G. The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal. Biochem Biophys Res Commun. 2015 Aug 7;463(4):1305-10.

Duval R, Fritsch L, Bui LC, Berthelet J, Guidez F, Mathieu C, Dupret JM, Chomienne C, Ait-Si-Ali S, Rodrigues-Lima F. An acetyltransferase assay for CREB-binding protein based on reverse phase-ultra-fast liquid chromatography of fluorescent histone H3 peptides. Anal Biochem. 2015 Oct 1;486:35-7.

Chan Ho Tong L, Dairou J, Bui LC, Bouillon J, Rodrigues-Lima F, Dupret JM, Silar P. Screen for soil fungi highly resistant to dichloroaniline uncovers mostly Fusarium species. Fungal Genet Biol. 2015 Aug;81:82-7.

Duval R, Bui LC, Berthelet J, Dairou J, Mathieu C, Guidez F, Dupret JM, Cools J, Chomienne C, Rodrigues-Lima F. A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2). Sci Rep. 2015 Jun 4;5:10750.

Juillerat-Jeanneret L, Dusinska M, Fjellsbø LM, Collins AR, Handy RD, Riediker M; NanoTEST Consortium. Biological impact assessment of nanomaterial used in nanomedicine. introduction to the NanoTEST project. Nanotoxicology. 2015 May;9 Suppl 1:5-12.

Cowie H, Magdolenova Z, Saunders M, Drlickova M, Correia Carreira S, Halamoda Kenzaoi B, Gombau L, Guadagnini R, Lorenzo Y, Walker L, Fjellsbø LM, Huk A, Rinna A, Tran L, Volkovova K, Boland S, Juillerat-Jeanneret L, Marano F, Collins AR, Dusinska M. Suitability of human and mammalian cells of different origin for the assessment of genotoxicity of metal and polymeric engineered nanoparticles. Nanotoxicology. 2015 May;9 Suppl 1:57-65.

Lavelle C, Busi F, Arluison V. Multiple approaches for the investigation of bacterial small regulatory RNAs self-assembly. Methods Mol Biol. 2015;1297:21-42.

Dusinska M, Boland S, Saunder M, Juillerat-Jeannere L, Tran L, Pojana G, Marcomini A, Volkovova K, Tulinska J, Knudsen LE,Gombau L, Whelan M, Collins AR, Halamoda Kenzaoui B, Correia Carreira S,  Marano F, Housiadas C, Bilanicova D, Magdolenova Z, Fjellsbø LM,  Huk A, Handy R, Barancokova M, Bartonova A, Burello E, Walker L, Castell J, Cowie H,  Drlickova M, Fernandez B, Guadagnini R, Harris G, Harju M, Heimstad ES, Hurbankova M, Kazimirova A, Kovacikova Z, Kuricova M, Liskova A, Milcamps A, Mose T, Neubauerova E, Palosaari T, Pilou M, Poulsen MS, Ross B, Runden-Pran E, Sebekova K, Staruchova M, Vallotto D, Worth A. Towards an alternative testing strategy for nanomaterials used in nanomedicine: Lessons from NanoTEST. Nanotoxicology. 2015 9(S1): 118–132.

George I, Naudin G, Boland S, Mornet S, Contremoulins V, Beugnon K, Martinon L, Lambert O, Baeza-Squiban A. Metallic oxide nanoparticle translocation across the human bronchial epithelial barrier. Nanoscale. 2015 Mar 14;7(10):4529-44.

Xu X, Li de la Sierra-Gallay I, Kubiak X, Duval R, Chaffotte AF, Dupret JM, Haouz A, Rodrigues-Lima F. Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A. Acta Crystallogr D Biol Crystallogr. 2015 Feb;71(Pt 2):266-73.

Delaval M, Boland S, Solhonne B, Nicola MA, Mornet S, Baeza-Squiban A, Sallenave JM, Garcia-Verdugo I. Acute exposure to silica nanoparticles enhances mortality and increases lung permeability in a mouse model of Pseudomonas aeruginosa pneumonia. Part Fibre Toxicol. 2015 Jan 21;12:1.

Richarme G, Mihoub M, Dairou J, Bui LC, Leger T, Lamouri A. Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues. J Biol Chem. 2015 Jan 16;290(3):1885-97.

Cayrol B, Fortas E, Martret C, Cech G, Kloska A, Caulet S, Barbet M, Trépout S, Marco S, Taghbalout A, Busi F, Wegrzyn G, Arluison V. Riboregulation of the bacterial actin-homolog MreB by DsrA small noncoding RNA. Integr Biol (Camb). 2015 Jan;7(1):128-41.

Mathieu C, Duval R, Xu X, Rodrigues-Lima F, Dupret JM. Effects of pesticide chemicals on the activity of metabolic enzymes: focus on thiocarbamates. Expert Opin Drug Metab Toxicol. 2015 Jan;11(1):81-94.

Gesbert G, Ramond E, Tros F, Dairou J, Frapy E, Barel M, Charbit A. Importance of branched-chain amino acid utilization in Francisella intracellular adaptation. Infect Immun. 2015 Jan;83(1):173-83.

Juricek L, Bui LC, Busi F, Pierre S, Guyot E, Lamouri A, Dupret JM, Barouki R, Coumoul X, Rodrigues-Lima F. Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites. Arch Toxicol. 2015 Dec;89(12):2403-12.

George I, Vranic S, Boland S, Courtois A, Baeza-Squiban A. Development of an in vitro model of human bronchial epithelial barrier to study nanoparticle translocation. Toxicol In Vitro. 2015 Feb;29(1):51-8.

Guadagnini R, Moreau K, Hussain S, Marano F, Boland S. Toxicity evaluation of engineered nanoparticles for medical applications using pulmonary epithelial cells. Nanotoxicology. 2015 May;9 Suppl 1:25-32.

Guadagnini R, Halamoda Kenzaoui B, Walker L, Pojana G, Magdolenova Z, Bilanicova D, Saunders M, Juillerat-Jeanneret L, Marcomini A, Huk A, Dusinska M, Fjellsbø LM, Marano F, Boland S. Toxicity screenings of nanomaterials: challenges due to interference with assay processes and components of classic in vitro tests. Nanotoxicology. 2015 May;9 Suppl 1:13-24.