Central Control of Feeding Behaviour and Energy Expenditure (C2OFFEE)

 

Selected publications

1/ Berland C, Castel J, Terrasi R, Montalban E, Foppen E, Martin C, Muccioli GG, Luquet S, Gangarossa G. Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis. Mol Psychiatry. 2022 Jan 20. doi: 10.1038/s41380-021-01428-z. Epub ahead of print. PMID: 35075269

2/ Berland C, Small DM, Luquet S, Gangarossa G. Dietary lipids as regulators of reward processes: multimodal integration matters. Trends Endocrinol Metab. 2021 Sep;32(9):693-705. doi: 10.1016/j.tem.2021.05.008. Epub 2021 Jun 17. PMID:34148784.

3/Berland C, Montalban E, Perrin E, Di Miceli M, Nakamura Y, Martinat M, Sullivan M, Davis XS, Shenasa MA, Martin C, Tolu S, Marti F, Caille S, Castel J, Perez S, Salinas CG, Morel C, Hecksher-Sørensen J, Cador M, Fioramonti X, Tschöp MH, Layé S, Venance L, Faure P, Hnasko TS, Small DM, Gangarossa G, Luquet SH. Circulating Triglycerides Gate Dopamine-Associated Behaviors through DRD2-Expressing Neurons. Cell Metab. 2020 Apr 7;31(4):773-790.e11. doi: 10.1016/j.cmet.2020.02.010. Epub 2020 Mar 5. PMID: 32142669; PMCID: PMC7250662.

http://www.cnrs.fr/fr/les-triglycerides-controlent-les-neurones-du-circuit-de-la-recompense

http://www.cnrs.fr/en/triglycerides-control-neurons-reward-circuit

https://theconversation.com/comment-le-gras-controle-les-neurones-du-plaisir-133035

4/ Denis RG, Joly-Amado A, Webber E, Langlet F, Schaeffer M, Padilla SL, Cansell C, Dehouck B, Castel J, Delbès AS, Martinez S, Lacombe A, Rouch C, Kassis N, Fehrentz JA, Martinez J, Verdié P, Hnasko TS, Palmiter RD, Krashes MJ, Güler AD, Magnan C, Luquet S. Palatability Can Drive Feeding Independent of AgRP Neurons. Cell Metab. 2015 Oct 6;22(4):646-57. doi: 10.1016/j.cmet.2015.07.011. Epub 2015 Aug 13. Erratum in: Cell Metab. 2017 Apr 4;25(4):975. PMID: 26278050; PMCID: PMC5024566.

5/ Cansell C, Castel J, Denis RG, Rouch C, Delbes AS, Martinez S, Mestivier D, Finan B, Maldonado-Aviles JG, Rijnsburger M, Tschöp MH, DiLeone RJ, Eckel RH, la Fleur SE, Magnan C, Hnasko TS, Luquet S. Dietary triglycerides act on mesolimbic structures to regulate the rewarding and motivational aspects of feeding. Mol Psychiatry. 2014 Oct;19(10):1095-105. doi: 10.1038/mp.2014.31. Epub 2014 Apr 15. PMID: 24732670; PMCID: PMC4303340.

 

Publications in peer-reviewed journals (since 2017)

 

** Publications shared with other teams of BFA.

Quartiles as from Scimago Journal & Country Rank are reported at the end of each publication.

 

Original articles

 

2024

 

Castel J, Li G, Onimus O, Leishman E, Cani PD, Bradshaw H, Mackie K, Everard A, Luquet S, Gangarossa G. NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis. Mol Psychiatry. 2024 Feb 15. (Q1)

 

Castell L, Le Gall V, Cutando L, Petit CP, Puighermanal E, Makrini-Maleville L, Kim HR, Jercog D, Tarot P, Tassou A, Harrus AG, Rubinstein M, Nouvian R, Rivat C, Besnard A, Trifilieff P, Gangarossa G, Janak PH, Herry C, Valjent E. Dopamine D2 receptors in WFS1 neurons regulate food-seeking and avoidance behaviors. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Feb 8;129:110883.

 

**Diepenbroek C, Rijnsburger M, van Irsen AAS, Eggels L, Kisner A, Foppen E, Unmehopa UA, Berland C, Dólleman S, Hardonk M, Cruciani-Guglielmacci C, Faust RP, Wenning R, Maya-Monteiro CM, Kalsbeek A, Aponte Y, Luquet S, Serlie MJM, la Fleur SE. Dopamine in the nucleus accumbens shell controls systemic glucose metabolism via the lateral hypothalamus and hepatic vagal innervation in rodents. Metabolism. 2024 Jan;150:155696.

 

 

2023

 

Slomp M, Koekkoek LL, Mutersbaugh M, Linville I, Luquet SH, la Fleur SE. Free-choice high-fat diet consumption reduces lateral hypothalamic GABAergic activity, without disturbing neural response to sucrose drinking in mice. Front Neurosci. 2023 Aug 3;17:1219569. (Q2)

 

Vivot K, Meszaros G, Pangou E, Zhang Z, Qu M, Erbs E, Yeghiazaryan G, Quiñones M, Grandgirard E, Schneider A, Clauss-Creusot E, Charlet A, Faour M, Martin C, Berditchevski F, Sumara I, Luquet S, Kloppenburg P, Nogueiras R, Ricci R. CaMK1D signalling in AgRP neurons promotes ghrelin-mediated food intake. Nat Metab. 2023 Jun;5(6):1045-1058. (Q1)

 

Delbès AS, Quiñones M, Gobet C, Castel J, Denis RGP, Berthelet J, Weger BD, Challet E, Charpagne A, Metairon S, Piccand J, Kraus M, Rohde BH, Bial J, Wilson EM, Vedin LL, Minniti ME, Pedrelli M, Parini P, Gachon F, Luquet S. Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior. Sci Adv. 2023 May 19;9(20):eadf2982. (Q1)

 

**Montalban E, Walle R, Castel J, Ansoult A, Hassouna R, Foppen E, Fang X, Hutelin Z, Mickus S, Perszyk E, Petitbon A, Berthelet J, Rodrigues-Lima F, Cebrian-Serrano A, Gangarossa G, Martin C, Trifilieff P, Bosch-Bouju C, Small DM, Luquet S. The Addiction Susceptibility TaqIA/Ankk1 Controls Reward and Metabolism Through D₂ Receptor-Expressing Neurons. Biol Psychiatry. 2023 Sep 1;94(5):424-436. (Q1)

 

Leuillier M, Duflot T, Ménoret S, Messaoudi H, Djerada Z, Groussard D, Denis RGP, Chevalier L, Karoui A, Panthu B, Thiébaut PA, Schmitz-Afonso I, Nobis S, Campart C, Henry T, Sautreuil C, Luquet SH, Beseme O, Féliu C, Peyret H, Nicol L, Henry JP, Renet S, Mulder P, Wan D, Tesson L, Heslan JM, Duché A, Jacques S, Ziegler F, Brunel V, Rautureau GJP, Monteil C, do Rego JL, do Rego JC, Afonso C, Hammock B, Madec AM, Pinet F, Richard V, Anegon I, Guignabert C, Morisseau C, Bellien J. CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury. J Adv Res. 2023 Jan;43:163-174. (Q1)

 

2022

 

Bakker W, Imbernon M, Salinas CG, Herrera Moro Chao D, Hassouna R, Morel C, Martin C, Leger C, Denis RGP, Castel J, Peter A, Heni M, Maetzler W, Nielsen HS, Duquenne M, Schwaninger M, Lundh S, Johan Hogendorf WF, Gangarossa G, Secher A, Hecksher-Sørensen J, Pedersen TÅ, Prevot V, Luquet S. Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis. Cell Rep. 2022 Nov 22;41(8):111698. Q1

 

**Herrera Moro Chao D, Kirchner MK, Pham C, Foppen E, Denis RGP, Castel J, Morel C, Montalban E, Hassouna R, Bui LC, Renault J, Mouffle C, García-Cáceres C, Tschöp MH, *Li D, Martin C, Stern JE, Luquet SH. Hypothalamic astrocytes control systemic glucose metabolism and energy balance. Cell Metab. 2022 Oct 4;34(10):1532-1547. Q1

 

Onimus Oriane, Emmanuel Valjent, Gilberto Fisone, Giuseppe Gangarossa. Haloperidol-Induced Immediate Early Genes in Striatopallidal Neurons Requires the Converging Action of cAMP/PKA/DARPP-32 and mTOR Pathways. Int J Mol Sci. 2022 Oct 1;23(19):11637. Q1

 

Huwart SJP, de Wouters d’Oplinter A, Rastelli M, Van Hul M, de Vos WM, Luquet S, Cani PD, Everard A. Food Reward Alterations during Obesity Are Associated with Inflammation in the Striatum in Mice: Beneficial Effects of <i>Akkermansia muciniphila</i>. Cells. 2022 Aug 16;11(16):2534. Q1

 

Imbernon M, Saponaro C, Helms HCC, Duquenne M, Fernandois D, Deligia E, Denis RGP, Herrera Moro Chao D, Rasika S, Staels B, Pattou F, Pfrieger FW, Brodin B, Luquet S, Bonner C, Prevot V. Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions. Cell Metab. 2022 Jun 14:S1550-4131(22)00222-4. Q1

Dumont C, Li G, Castel J, Luquet S, Gangarossa G. Hindbrain catecholaminergic inputs to the paraventricular thalamus scale feeding and metabolic efficiency in stress-related contexts. J Physiol. 2022 Jun;600(12):2877-2895. Q1

 

**Joly-Amado A, Soty M, Philippe E, Lacombe A, Castel J, Pillot B, Vily-Petit J, Zitoun C, Mithieux G, Magnan C. Portal Glucose Infusion, Afferent Nerve Fibers, and Glucose and Insulin Tolerance of Insulin-Resistant Rats. J Nutr. 2022 May 2:nxac097. Q1

 

Berland C, Castel J, Terrasi R, Montalban E, Foppen E, Martin C, Muccioli GG, Luquet S, Gangarossa G. Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis. Mol Psychiatry. 2022 Jan 20. Q1

 

Brito V, Montalban E, Sancho-Balsells A, Pupak A, Flotta F, Masana M, Ginés S, Alberch J, Martin C, Girault J-A, Giralt A Hippocampal Egr1-dependent neuronal ensembles negatively regulate motor learning. J Neuroscience 2022 42 (27) 5346-5360 Q1

 

Montalban E, Giralt A, Taing L, Schut EHS, Supiot LF, Castell L, Nakamura Y, de Pins B, Pelosi A, Goutebroze L, Tuduri P, Wang W, Neiburga KD, Vestito L, Castel J, Luquet S, Nairn AC, Hervé D, Heintz N, Martin C, Greengard P, Valjent E, Meye FJ, Gambardella N, Roussarie JP, Girault JA. Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal prostaglandin E2 modulatory effects. Mol Psychiatry. 2022 Feb 18. Q1

 

Pramfalk C, Ahmed O, Pedrelli M, Minniti ME, Luquet S, Denis RG, Olin M, Härdfeldt J, Vedin LL, Steffensen KR, Rydén M, Hodson L, Eriksson M, Parini P. Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice. J Intern Med. 2022 Jan 4. Q1

Linsambarth S, Carvajal FJ, Moraga-Amaro R, Mendez L, Tamburini G, Jimenez I, Verdugo DA, Gómez GI, Jury N, Martínez P, van Zundert B, Varela-Nallar L, Retamal MA, Martin C, Altenberg GA, Fiori MC, Cerpa W, Orellana JA, Stehberg J. Astroglial gliotransmitters released via Cx43 hemichannels regulate NMDAR-dependent transmission and short-term fear memory in the basolateral amygdala. FASEB J. 2022 Feb;36(2):e22134. Q1

 

2021

 

Marion C, Zizzari P, Denis RG, Hassouna R, Chebani Y, Leste-Lasserre T, Doat H, Le Pen G, Cota D, Noble F, Luquet S, Pantel J. The GhsrQ343X allele favors the storage of fat by acting on nutrient partitioning. J Endocrinol. 2021 Sep 1:JOE-20-0576.R2. Q2

Cornejo MP, Denis RGP, García Romero G, Fernández G, Reynaldo M, Luquet S, Perello M. Ghrelin treatment induces rapid and delayed increments of food intake: a heuristic model to explain ghrelin’s orexigenic effects. Cell Mol Life Sci. 2021 Oct;78(19-20):6689-6708. Q1

Koekkoek LL, Slomp M, Castel J, Mutersbaugh M, Linville I, Serlie MJ, Luquet SH, la Fleur SE. Disruption of lateral hypothalamic calorie detection by a free choice high fat diet. FASEB J. 2021 Sep;35(9):e21804. Q1

Just PA, Charawi S, Denis RGP, Savall M, Traore M, Foretz M, Bastu S, Magassa S, Senni N, Sohier P, Wursmer M, Vasseur-Cognet M, Schmitt A, Le Gall M, Leduc M, Guillonneau F, De Bandt JP, Mayeux P, Romagnolo B, Luquet S, Bossard P, Perret C. Author Correction: Lkb1 suppresses amino acid-driven gluconeogenesis in the liver. Nat Commun. 2021 Mar 17;12(1):1831. doi: 10.1038/s41467-021-22104-4. Erratum for: Nat Commun. 2020 Nov 30;11(1):6127. Q1

Dalenberg JR, Denis R, Luquet S, Small DM. Further Evidence that Habitual Consumption of Sucralose with, but Not without, Carbohydrate Alters Glucose Metabolism. Cell Metab. 2021 Feb 2;33(2):227-228. Q1

Prola A, Blondelle J, Vandestienne A, Piquereau J, Denis RGP, Guyot S, Chauvin H, Mourier A, Maurer M, Henry C, Khadhraoui N, Gallerne C, Molinié T, Courtin G, Guillaud L, Gressette M, Solgadi A, Dumont F, Castel J, Ternacle J, Demarquoy J, Malgoyre A, Koulmann N, Derumeaux G, Giraud MF, Joubert F, Veksler V, Luquet S, Relaix F, Tiret L, Pilot-Storck F. Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle. Sci Adv. 2021 Jan 1;7(1):eabd6322. Q1

Tirou L, Russo M, Faure H, Pellegrino G, Demongin C, Daynac M, Sharif A, Amosse J, Le Lay S, Denis R, Luquet S, Taouis M, Benomar Y, Ruat M. Sonic Hedgehog receptor Patched deficiency in astrocytes enhances glucose metabolism in mice. Mol Metab. 2021 May;47:101172. Q1

Favier M, Pietrancosta N, El Mestikawy S, Gangarossa G. Leveraging VGLUT3 Functions to Untangle Brain Dysfunctions. Trends Pharmacol Sci. 2021 Jun;42(6):475-490. Q1

Forner-Piquer I, Klement W, Gangarossa G, Zub E, de Bock F, Blaquiere M, Maurice T, Audinat E, Faucherre A, Lasserre F, Ellero-Simatos S, Gamet-Payrastre L, Jopling C, Marchi N. Varying modalities of perinatal exposure to a pesticide cocktail elicit neurological adaptations in mice and zebrafish. Environ Pollut. 2021 Jun 1;278:116755. Q1

Valjent E, Gangarossa G. The Tail of the Striatum: From Anatomy to Connectivity and Function. Trends Neurosci. 2021 Mar;44(3):203-214. Q1

 

2020

 

Just PA, Charawi S, Denis RGP, Savall M, Traore M, Foretz M, Bastu S, Magassa S, Senni N, Sohier P, Wursmer M, Vasseur-Cognet M, Schmitt A, Le Gall M, Leduc M, Guillonneau F, De Bandt JP, Mayeux P, Romagnolo B, Luquet S, Bossard P, Perret C. Lkb1 suppresses amino acid-driven gluconeogenesis in the liver. Nat Commun. 2020 Nov 30;11(1):6127. Erratum in: Nat Commun. 2021 Mar 17;12(1):1831. Q1

Gangarossa G, Perez S, Dembitskaya Y, Prokin I, Berry H, Venance L. BDNF Controls Bidirectional Endocannabinoid Plasticity at Corticostriatal Synapses. Cereb Cortex. 2020 Jan 10;30(1):197-214. Q1

Nuzzaci D, Cansell C, Liénard F, Nédélec E, Ben Fradj S, Castel J, Foppen E, Denis R, Grouselle D, Laderrière A, Lemoine A, Mathou A, Tolle V, Heurtaux T, Fioramonti X, Audinat E, Pénicaud L, Nahon JL, Rovère C, Benani A. Postprandial Hyperglycemia Stimulates Neuroglial Plasticity in Hypothalamic POMC Neurons after a Balanced Meal. Cell Rep. 2020 Mar 3;30(9):3067-3078.e5. Q1

 

Schriever SC, Kabra DG, Pfuhlmann K, Baumann P, Baumgart EV, Nagler J, Seebacher F, Harrison L, Irmler M, Kullmann S, Corrêa-da-Silva F, Giesert F, Jain R, Schug H, Castel J, Martinez S, Wu M, Häring HU, de Angelis MH, Beckers J, Müller TD, Stemmer K, Wurst W, Rozman J, Nogueiras R, De Angelis M, Molkentin JD, Krahmer N, Yi CX, Schmidt MV, Luquet S, Heni M, Tschöp MH, Pfluger PT. Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity. J Clin Invest. 2020 Nov 2;130(11):6093-6108. Q1

Rastelli M, Van Hul M, Terrasi R, Lefort C, Régnier M, Beiroa D, Delzenne NM, Everard A, Nogueiras R, Luquet S, Muccioli GG, Cani PD. Intestinal NAPE-PLD contributes to short-term regulation of food intake via gut-to-brain axis. Am J Physiol Endocrinol Metab. 2020 Sep 1;319(3):E647-E657. Q1

**Amouyal C, Castel J, Guay C, Lacombe A, Denom J, Migrenne-Li S, Rouault C, Marquet F, Georgiadou E, Stylianides T, Luquet S, Le Stunff H, Scharfmann R, Clément K, Rutter GA, Taboureau O, Magnan C, Regazzi R, Andreelli F. A surrogate of Roux-en-Y gastric bypass (the enterogastro anastomosis surgery) regulates multiple beta-cell pathways during resolution of diabetes in ob/ob mice. EBioMedicine. 2020 Aug;58:102895. Q1

Pham C, Moro DH, Mouffle C, Didienne S, Hepp R, Pfrieger FW, Mangin JM, Legendre P, Martin C, Luquet S, Cauli B, Li D. Mapping astrocyte activity domains by light sheet imaging and spatio-temporal correlation screening. Neuroimage. 2020 Oct 15;220:117069. Q1

 

Valverde S, Vandecasteele M, Piette C, Derousseaux W, Gangarossa G, Aristieta Arbelaiz A, Touboul J, Degos B, Venance L. Deep brain stimulation- guided optogenetic rescue of parkinsonian symptoms. Nat Commun. 2020 May 13;11(1):2388. Q1

Lefort C, Roumain M, Van Hul M, Rastelli M, Manco R, Leclercq I, Delzenne NM, Marzo VD, Flamand N, Luquet S, Silvestri C, Muccioli GG, Cani PD. Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism. Cells. 2020 May 18;9(5):1247. Q2

**Filipe A, Chernorudskiy A, Arbogast S, Varone E, Villar-Quiles RN, Pozzer D, Moulin M, Fumagalli S, Cabet E, Dudhal S, De Simoni MG, Denis RG, Vadrot N, Dill C, Giovarelli M, Szweda L, De Palma C, Pinton P, Giorgi C, Viscomi C, Clementi E, Missiroli S, Boncompagni S, Zito E, Ferreiro A. Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy. Cell Death Differ. 2020 Jul 13. Q1.

 

Berland C, Montalban E, Perrin E, Di Miceli M, Nakamura Y, Martinat M, Sullivan M, Davis XS, Shenasa MA, Martin C, Tolu S, Marti F, Caille S, Castel J, Perez S, Salinas CG, Morel C, Hecksher-Sørensen J, Cador M, Fioramonti X, Tschöp MH, Layé S, Venance L, Faure P, Hnasko TS, Small DM, Gangarossa G, Luquet SH. Circulating Triglycerides Gate Dopamine-Associated Behaviors through DRD2-Expressing Neurons. Cell Metab. 2020 Apr 7;31(4):773-790.e11. Q1

Dalenberg JR, Patel BP, Denis R, Veldhuizen MG, Nakamura Y, Vinke PC, Luquet S, Small DM. Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans. Cell Metab. 2020 Mar 3;31(3):493-502.e7. Q1

Minniti ME, Pedrelli M, Vedin LL, Delbès AS, Denis RGP, Öörni K, Sala C, Pirazzini C, Thiagarajan D, Nurmi HJ, Grompe M, Mills K, Garagnani P, Ellis ECS, Strom SC, Luquet SH, Wilson EM, Bial J, Steffensen KR, Parini P. Insights From Liver-Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR-Agonist Pharmacodynamics in Humans. Hepatology. 2020 Aug;72(2):656-670. Q1

Klement W, Oliviero F, Gangarossa G, Zub E, De Bock F, Forner-Piquer I, Blaquiere M, Lasserre F, Pascussi JM, Maurice T, Audinat E, Ellero-Simatos S, Gamet-Payrastre L, Mselli-Lakhal L, Marchi N. Life-long Dietary Pesticide Cocktail Induces Astrogliosis Along with Behavioral Adaptations and Activates p450 Metabolic Pathways. Neuroscience. 2020 Oct 15;446:225-237. Q1

Gourévitch B, Martin C, Postal O, Eggermont JJ. Oscillations in the auditory system and their possible role. Neurosci Biobehav Rev. 2020 Jun;113:507-528. Q3

 

2019

Al-Massadi O, Quiñones M, Clasadonte J, Hernandez-Bautista R, Romero-Picó A, Folgueira C, Morgan DA, Kalló I, Heras V, Senra A, Funderburk SC, Krashes MJ, Souto Y, Fidalgo M, Luquet S, Chee MJ, Imbernon M, Beiroa D, García-Caballero L, Gallego R, Lam BYH, Yeo G, Lopez M, Liposits Z, Rahmouni K, Prevot V, Dieguez C, Nogueiras R. MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance. Diabetes. 2019 Dec;68(12):2210-2222. Q1

de Lombares C, Heude E, Alfama G, Fontaine A, Hassouna R, Vernochet C, de Chaumont F, Olivo-Marin C, Ey E, Parnaudeau S, Tronche F, Bourgeron T, Luquet S, Levi G, Narboux-Nême N. Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan. Aging (Albany NY). 2019 Sep 12;11(17):6638-6656. Q1

** Denis RGP, Busi F, Castel J, Morel C, Zhang W, Bui LC, Sugamori KS, Prokopec SD, Boutros PC, Grant DM, Rodrigues-Lima F, Luquet S, Dupret JM. A readout of metabolic efficiency in arylamine N-acetyltransferase-deficient mice reveals minor energy metabolism changes. FEBS Lett. 2019 Apr;593(8):831-841. Q2

Everard A, Plovier H, Rastelli M, Van Hul M, de Wouters d’Oplinter A, Geurts L, Druart C, Robine S, Delzenne NM, Muccioli GG, de Vos WM, Luquet S, Flamand N,  Di Marzo V, Cani PD. Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis. Nat Commun. 2019 Jan 28;10(1):457. Q1

Gangarossa G, Castell L, Castro L, Tarot P, Veyrunes F, Vincent P, Bertaso F, Valjent E. Contrasting patterns of ERK activation in the tail of the striatum in response to aversive and rewarding signals. J Neurochem. 2019 Oct;151(2):204-226. Q1

Mansouri-Guilani N, Bernard V, Vigneault E, Vialou V, Daumas S, El Mestikawy S, Gangarossa G. VGLUT3 gates psychomotor effects induced by amphetamine. J Neurochem. 2019 Mar;148(6):779-795. Q1

Valjent E, Biever A, Gangarossa G, Puighermanal E. Dopamine signaling in the striatum. Adv Protein Chem Struct Biol. 2019;116:375-396. Q3

**London J, Ndiaye FK, Bui LC, Souchet B, Daubigney F, Magnan C, Luquet S, Dairou J, Janel N, Rouch C. Alterations in the Serotonin and Dopamine Pathways by Cystathionine Beta Synthase Overexpression in Murine Brain. Mol Neurobiol. 2019 Jun;56(6):3958-3971. Q1

**Dalle H, Garcia M, Antoine B, Boehm V, Do TTH, Buyse M, Ledent T, Lamazière A, Magnan C, Postic C, Denis RG, Luquet S, Fève B, Moldes M. Adipocyte Glucocorticoid Receptor Deficiency Promotes Adipose Tissue Expandability and Improves the Metabolic Profile Under Corticosterone Exposure. Diabetes. 2019 Feb;68(2):305-317. Q1

**Mortreux M, Foppen E, Denis RG, Montaner M, Kassis N, Denom J, Vincent M, Fumeron F, Kujawski-Lafourcade M, Andréelli F, Balkau B, Marre M, Roussel R, Magnan C, Gurden H, Migrenne-Li S. New roles for prokineticin 2 in feeding behavior, insulin resistance and type 2 diabetes: Studies in mice and humans. Mol Metab. 2019 Nov;29:182-196. Q1

 

**Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G. Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. Cell Metab. 2019 Oct 1;30(4):754-767.e9. Q1

 

**Gnaedinger A, Gurden H, Gourévitch B, Martin C. Multisensory learning between odor and sound enhances beta oscillations. Sci Rep. 2019 Aug 2;9(1):11236. Q1

Bryche B, Le Bourhis M, Congar P, Martin C, Rampin O, Meunier N. Endothelin impacts on olfactory processing in rats. Behav Brain Res. 2019 Apr 19;362:1-6. Q2

 

2018

 

Boussadia B, Lakhal L, Payrastre L, Ghosh C, Pascussi JM, Gangarossa G, Marchi N. Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity. Neuroscience. 2018 Feb 1;370:130-138. Q2

Péterfi Z, Farkas I, Denis RGP, Farkas E, Uchigashima M, Füzesi T, Watanabe M, Lechan RM, Liposits Z, Luquet S, Fekete C. Endocannabinoid and nitric oxide systems of the hypothalamic paraventricular nucleus mediate effects of NPY on energy expenditure. Mol Metab. 2018 Dec;18:120-133. Q1

Delbès AS, Castel J, Denis RGP, Morel C, Quiñones M, Everard A, Cani PD, Massiera F, Luquet SH. Prebiotics Supplementation Impact on the Reinforcing and Motivational Aspect of Feeding. Front Endocrinol (Lausanne). 2018 May 29;9:273. Q1

Laurans L, Venteclef N, Haddad Y, Chajadine M, Alzaid F, Metghalchi S, Sovran B, Denis RGP, Dairou J, Cardellini M, Moreno-Navarrete JM, Straub M, Jegou S, McQuitty C, Viel T, Esposito B, Tavitian B, Callebert J, Luquet SH, Federici M, Fernandez-Real JM, Burcelin R, Launay JM, Tedgui A, Mallat Z, Sokol H, Taleb S. Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. Nat Med. 2018 Aug;24(8):1113-1120. Q1

Reichenbach A, Stark R, Mequinion M, Lockie SH, Lemus MB, Mynatt RL, Luquet S, Andrews ZB. Carnitine acetyltransferase (Crat) in hunger-sensing AgRP neurons permits adaptation to calorie restriction. FASEB J. 2018 Jun 22:fj201800634R. Q1

**London J, Rouch C, Bui LC, Assayag E, Souchet B, Daubigney F, Medjaoui H, Luquet S, Magnan C, Delabar JM, Dairou J, Janel N. Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues. Mol Neurobiol. 2018 May;55(5):3822-3831. Q1

**Laperrousaz E, Denis RG, Kassis N, Contreras C, López M, Luquet S, Cruciani-Guglielmacci C, Magnan C. Lipoprotein Lipase Expression in Hypothalamus Is Involved in the Central Regulation of Thermogenesis and the Response to Cold Exposure. Front Endocrinol (Lausanne). 2018 Mar 14;9:103. Q1

Reichenbach A, Stark R, Mequinion M, Denis RRG, Goularte JF, Clarke RE, Lockie SH, Lemus MB, Kowalski GM, Bruce CR, Huang C, Schittenhelm RB, Mynatt RL, Oldfield BJ, Watt MJ, Luquet S, Andrews ZB. AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning. Cell Rep. 2018 Feb 13;22(7):1745-1759. Q1

**Fructuoso M, Rachdi L, Philippe E, Denis RG, Magnan C, Le Stunff H, Janel N, Dierssen M. Corrigendum to « Increased levels of inflammatory plasma markers and obesity risk in a mouse model of Down syndrome » [Free Radic. Biol. Med. 114 (2018) 122-130]. Free Radic Biol Med. 2018 Apr;118:150. Q1

 

2017

Goupille O, Penglong T, Kadri Z, Granger-Locatelli M, Denis R, Luquet S, Badoual C, Fucharoen S, Maouche-Chrétien L, Leboulch P, Chrétien S. The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis. Cell Rep. 2017 Dec 19;21(12):3524-3535. Q1

**Gao Y, Layritz C, Legutko B, Eichmann TO, Laperrousaz E, Moullé VS, Cruciani-Guglielmacci C, Magnan C, Luquet S, Woods SC, Eckel RH, Yi CX, Garcia-Caceres C, Tschöp MH. Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity. Diabetes. 2017 Oct;66(10):2555-2563. Q1

**Rijnsburger M, Eggels L, Castel J, Cruciani-Guglielmacci C, Ackermans MT, Luquet S, la Fleur SE. A novel, double intra-carotid cannulation technique to study the effect of central nutrient sensing on glucose metabolism in the rat. J Neurosci Methods. 2017 Oct 1;290:79-84. Q3

**Laperrousaz E, Moullé VS, Denis RG, Kassis N, Berland C, Colsch B, Fioramonti X, Philippe E, Lacombe A, Vanacker C, Butin N, Bruce KD, Wang H, Wang Y, Gao Y, Garcia-Caceres C, Prévot V, Tschöp MH, Eckel RH, Le Stunff H, Luquet S, Magnan C, Cruciani-Guglielmacci C. Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice. Diabetologia. 2017 Jul;60(7):1314-1324. Q1

**Denis RGP, Joly-Amado A, Webber E, Langlet F, Schaeffer M, Padilla SL, Cansell C, Dehouck B, Castel J, Delbès AS, Martinez S, Lacombe A, Rouch C, Kassis N, Fehrentz JA, Martinez J, Verdié P, Hnasko TS, Palmiter RD, Krashes MJ, Güler AD, Magnan C, Luquet S. Palatability Can Drive Feeding Independent of AgRP Neurons. Cell Metab. 2017 Apr 4;25(4):975. Q1

Dalvi PS, Chalmers JA, Luo V, Han DY, Wellhauser L, Liu Y, Tran DQ, Castel J, Luquet S, Wheeler MB, Belsham DD. High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons. Int J Obes (Lond). 2017 Jan;41(1):149-158. Q2

Boussadia B, Lakhal L, Payrastre L, Ghosh C, Pascussi JM, Gangarossa G,Marchi N. Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity. Neuroscience. 2018 Feb 1;370:130-138. doi: 10.1016/j.neuroscience.2017.07.038. Epub 2017 Jul 23. PMID: 28743453; PMCID: PMC6247422. Q1

Senova S, Scisniak I, Chiang CC, Doignon I, Palfi S, Chaillet A, Martin C, Pain F. Experimental assessment of the safety and potential efficacy of high irradiance photostimulation of brain tissues. Sci Rep. 2017 Mar 9;7:43997. doi: 10.1038/srep43997. Erratum in: Sci Rep. 2017 Apr 07;7:46199. PMID: 28276522; PMCID: PMC5343659. Q1

**Chelminski Y, Magnan C, Luquet S, Everard A, Meunier N, Gurden H, Martin C. Odor-induced neuronal rhythms in the olfactory bulb are profoundly modified in ob/ob obese mice. Front Physiol. . 2017 Jan 19;8:2. Q1

 

Reviews

 

Al-Massadi O, Parini P, Fernø J, Luquet S, Quiñones M. Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system. Rev Endocr Metab Disord. 2022 Jun 10. doi: 10.1007/s11154-022-09732-x. PMID: 35687272. Q1

 

Luquet S, Gangarossa G. Dopamine drives food craving during pregnancy. Nat Metab. 2022 Apr;4(4):410-411. doi: 10.1038/s42255-022-00555-3. PMID: 35379971. Q1

 

**Faour M, Magnan C, *Gurden H, *Martin C. Olfaction in the context of obesity and diabetes: Insights from animal models to humans. Neuropharmacology. 2021 Dec 15;206:108923. doi: 10.1016/j.neuropharm.2021.108923. PMID: 34919903. Q1

Yeo GSH, Chao DHM, Siegert AM, Koerperich ZM, Ericson MD, Simonds SE, Larson CM, Luquet S, Clarke I, Sharma S, Clément K, Cowley MA, Haskell-Luevano C, Van Der Ploeg L, Adan RAH. The melanocortin pathway and energy homeostasis: From discovery to obesity therapy. Mol Metab. 2021 Jun;48:101206. doi: 10.1016/j.molmet.2021.101206. Epub 2021 Mar 6. PMID: 33684608; PMCID: PMC8050006. Q1

Berland C, Small DM, Luquet S*, Gangarossa G*. Dietary lipids as regulators of reward processes: multimodal integration matters. Trends Endocrinol Metab. 2021 Sep;32(9):693-705. doi: 10.1016/j.tem.2021.05.008. Epub 2021 Jun 17. PMID: 34148784. Q1

Gangarossa G*, Luquet S*. Hypothalamic Regulation of Glucose Homeostasis: Is the Answer in the Matrix? Cell Metab. 2020 Nov 3;32(5):701-703. doi: 10.1016/j.cmet.2020.10.003. PMID: 33147483. Q1

Luquet SH, Vaudry H, Granata R. Editorial: Neuroendocrine Control of Feeding Behavior. Front Endocrinol (Lausanne). 2019 Jun 19;10:399. Q1

 

García-Cáceres C, Balland E, Prevot V, Luquet S, Woods SC, Koch M, Horvath TL, Yi CX, Chowen JA, Verkhratsky A, Araque A, Bechmann I, Tschöp MH. Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism. Nat Neurosci. 2019 Jan;22(1):7-14. Q1

 

Abumrad NA, Amri EZ, Luquet S, Forest C. Pleiotropic physiological roles of PPARs and fatty acids: A tribute to Paul Grimaldi. Biochimie. 2017 May;136:1-2.

 

Sun X, Luquet S, Small DM. DRD2: Bridging the Genome and Ingestive Behavior. Trends Cogn Sci. 2017 May;21(5):372-384. Q1