Dr. Anne Laurençon
Equipe Vieillissement, reproduction et métabolisme, IGFL – Institut de Génomique Fonctionnelle de Lyon
Titre : Crosstalks between reproduction and longevity in C. elegans.
Date : Jeudi 16 mars 2017 à 12h00.
Lieu : Salle des séminaires de l’Institut Jacques Monod, Bâtiment Buffon, 15 rue Hélène Brion, pièce RdC Bas 18B, Université Paris Diderot, campus PRG
Invitée par : Dr. Hervé Tricoire, Equipe Processus dégénératifs, stress et vieillissement
Résumé
I will present data from the Aguilaniu group questioning the links between soma and germ line in C.elegans. During adulthood, the major energy stores should be mobilized rapidly to sustain one of the most energy demanding process: reproduction. In other words, reproduction is favored by the energy production systems over self-maintenance. This has been theorized long ago and is expected from an evolutionary point of view. Although the links between fat metabolism, reproduction, nutrition and longevity are many, no work is clearly addressing how these connections are regulated. Our data points to a single lipase which activity directly links lifespan extension and TAG consumption under dietary restriction.
